Clinical Results

A third party testing laboratory assessed 37 Extreme Actives in clinical trials, using objective tools designed to quantitatively measure changes in the multiple categories of cosmetic skin aging. The results of these independent studies demonstrated statistically significant decreases in the appearance of fine lines and wrinkles, the appearance of cosmetic blotches, and skin tone using objective clinical measures by computer analysis. In addition, not one case of irritation from 37 Actives was observed, demonstrating excellent tolerability in all skin types.

37 Actives is the first cream in the cosmetic realm to conduct post-market testing of the activity of the actives, shown to maintain 100% antioxidant activity to 6 months after jar opening and to maintain virtually all of actives at original levels up to 3 years post-manufacture (see below).

The over 37 actives in this highly advanced cream are the culmination of the very best scientific research from the lab, proven to also work on a clinical level, so that this one pot delivers results in all aspects of skin health, and systematically helps address the appearance of the many cosmetic changes of the skin over time.


Wrinkle Appearance Reduction

When measurements taken after 4, 6 and 8 weeks of product use were compared with baseline measurements, there was:

  • An 8.5% decrease (improvement) in the appearance of crow’s feet fine line / wrinkles after 4 weeks of product use;
  • A 17.0% decrease (improvement) in the appearance of crow’s feet fine line / wrinkles after 6 weeks of product use; and
  • A 17.0% decrease (improvement) in the appearance of crow’s feet fine line / wrinkles after 8 weeks of product use.

Appearance of Red Blotches Reduction

When measurements taken after 4, 6 and 8 weeks of product use were compared with baseline measurements, there was:
  • A 4.7% decrease (improvement) in the appearance of red blotchy skin after 4 weeks of product use;
  • A 6.4% decrease (improvement) in the appearance of red blotchy skin after 6 weeks of product use; and
  • A 10.9% decrease (improvement) in the appearance of red blotchy skin after 8 weeks of product use.

Appearance of Brown Blotches Reduction

When images taken after 4, 6 and 8 weeks of product use were compared with baseline images, there was:

  • A 1.1% improvement in brown blotchy skin after 4 weeks of product use;
  • A 2.1% improvement in brown blotchy skin after 6 weeks of product use; and
  • A 3.4% improvement in brown blotchy skin after 8 weeks of product use.

Laboratory Results

Antioxidant Activity



Extreme Active maintains 100% antioxidant activity 6 months after you open your jar.  100% of the actives are maintained at original levels out to 2 years.  



Competitors lose 50% of their antioxidant capability at 6 months and some creams have no actives, only preservative left at 1 year.


Safety

A third party laboratory tested the product for safety, showing not a single irritation reaction in any patient across the 35 subject study.

Competitors lose 50% of their antioxidant capability at 6 months and some creams have no actives, only preservative left at 1 year.

 


Published Clinical Trials

37 Extreme Actives was tested in an institutional review board approved clinical trial and published in the Journal of Drugs in Dermatology. 

Baseline (Left) and 1 Month (Right) Follow-Up Clinical Photographs Following Application of 37 Extreme Actives high performance anti-aging cream and Impact.